Published Articles
Park Ave Clinical Journal
Long-form clinical briefs from the Park Ave editorial team. Every article is authored by a member of the Clinical Review Board and reviewed under our documented methodology.
Endocrinology · November 2024
GLP-1 Receptor Agonists: A Comparative Mechanism Review
A side-by-side review of semaglutide, tirzepatide, and retatrutide — receptor activity, pharmacokinetics, and the distinguishing features of dual and triple-receptor agonism.
Quality & Documentation · November 2024
How to Read a Peptide Certificate of Analysis
A practitioner-level walkthrough of every section of a peptide COA — identity testing, HPLC purity, mass spectrometry, water and acetate content, endotoxin, bioburden, and storage attestations.
Regenerative Medicine · October 2024
BPC-157 and TB-500 in the Regenerative Literature
The preclinical body of evidence behind two of the most-referenced regenerative peptides, the proposed signaling pathways, and the open questions remaining in the research record.
Mitochondrial & Longevity · October 2024
Mitochondrial-Targeted Peptides: SS-31, MOTS-c, and the Energetic Hypothesis
How cardiolipin-binding peptides and mitochondrial-derived peptides interact with bioenergetics, oxidative stress, and the cellular senescence pathway.
Endocrinology · September 2024
Growth Hormone Axis Peptides: A Modern Review
GHRH analogs, GHRPs, and IGF-1 LR3 — distinguishing the secretagogue families, their receptor targets, and the differences between Tesamorelin, CJC-1295, and Ipamorelin.
Neuroscience · September 2024
Neuropeptides in Cognitive Research: Selank, Semax, and DSIP
The Russian-developed regulatory peptides, their proposed mechanisms in cognitive and mood research, and how the published record compares across the three compounds.
Quality & Documentation · August 2024
Storage and Handling: A Lab Reference for Peptide Stability
Lyophilized vs reconstituted stability, recommended diluents, light and temperature sensitivity, and the documentation chain that supports a stability claim.
Immune · August 2024
Thymosin Alpha-1 in Immune Modulation Research
Mechanism of action, clinical research record across viral and oncology contexts, and how the peptide is positioned in modern immunomodulation literature.
Neuroscience · July 2024
The Melanocortin System: PT-141 and Melanotan II in the Literature
A receptor-by-receptor look at the melanocortin pathway, the distinguishing pharmacology of PT-141 and Melanotan II, and the current research record on each.
Mitochondrial & Longevity · July 2024
Epitalon, Telomerase, and the Senescence Literature
A review of the published work on Epitalon, including the Russian-language source studies, the proposed telomerase mechanism, and what the wider longevity literature does and does not show.
Endocrinology · June 2024
Cagrilintide and Amylin Pharmacology in Metabolic Research
How long-acting amylin analogs complement incretin pharmacology, the receptor biology, and the recent combination trials with semaglutide.
Quality & Documentation · June 2024
Reading the Research Record: Evaluating Peptide Evidence
A practical framework for distinguishing primary preclinical work, secondary reviews, and clinical evidence in the peptide literature — and what to weigh each at.
Editorial Governance
Articles are reviewed by the Clinical Review Board and published under our editorial methodology.