Park Ave Peptides — Clinical Reference Library — For Professional Use Only

Musculoskeletal Research
Reference Compound
Educational reference for Follistatin-344. Scroll down for molecular profile, pharmacokinetics, mechanism, applications, and handling.
At a Glance
Quality Documentation
Lot PAP-FOLLIS-240118-A01 — Reference
Field of Medicine — Musculoskeletal Research
Musculoskeletal Research and Regenerative Biology.
Follistatin-344 is one of several naturally occurring isoforms of the follistatin glycoprotein, a high-affinity antagonist of TGF-β-family ligands including myostatin and activin A. It is widely studied as a tool compound for myostatin-pathway research.
Follistatin sequesters myostatin (GDF-8) and activin, neutralizing their inhibitory signaling at the ActRIIB receptor and removing a brake on skeletal-muscle growth. The 344-residue isoform has a heparin-binding tail that associates with cell-surface proteoglycans.
Reference Compound
Follistatin-344
02 — Science
03 — Pathway
Mechanism summaries for Follistatin-344 are drawn from peer-reviewed literature describing receptor binding, signaling pathways, and observed activity in preclinical models.
04 — Lab Reference
For licensed research and clinical evaluation only. Not dosing guidance.
Reconstitution
Bacteriostatic water (0.9% benzyl alcohol) or sterile water. Add diluent slowly along the vial wall — do not inject directly onto the lyophilized cake. Swirl gently until fully dissolved.
Storage
Lyophilized: −20°C long term; 2–8°C short term (weeks). Protect from light.Reconstituted: 2–8°C, generally up to 14–28 days depending on compound.
Quality
≥99% purity by HPLC. Identity confirmed by mass spectrometry. Independent third-party verification on every lot. COA available per lot.
Handling notes —Avoid repeated freeze–thaw cycles. Do not shake vigorously after reconstitution.
Need a full protocol brief?
Reconstitution worksheets, concentration reference cards, and sample COA for verified accounts.
05 — Comparative
See molecular profile, pharmacokinetics, and handling next to related compounds in the same family.
06 — Citations
The following sources are representative of the literature describing Follistatin-344. A full annotated citation list with PubMed identifiers is available on request.
See also the glossary of research terms and the full peptide library.
cGMP facility · Third-party tested · Cold-chain shipping · 24-hour COA on request