Park Ave Peptides — Clinical Reference Library — For Professional Use Only

Dermatology · Pigmentation Research
Reference Compound
Educational reference for Melanotan II. Scroll down for molecular profile, pharmacokinetics, mechanism, applications, and handling.
At a Glance
Quality Documentation
Lot PAP-MELANO-240118-A01 — Reference
Field of Medicine — Dermatology · Pigmentation Research
Dermatology and Melanocortin-System Research.
Melanotan II is a synthetic cyclic heptapeptide analog of α-MSH originally developed at the University of Arizona as a research tool for melanocortin-receptor pharmacology and photoprotection studies.
Melanotan II is a non-selective agonist at MC1R, MC3R, MC4R, and MC5R. MC1R activation drives eumelanin production in melanocytes; MC4R activation in CNS nuclei influences appetite and sexual arousal pathways, accounting for the breadth of its observed effects.
Reference Compound
Melanotan II
02 — Science
03 — Pathway
Mechanism summaries for Melanotan II are drawn from peer-reviewed literature describing receptor binding, signaling pathways, and observed activity in preclinical models.
04 — Lab Reference
For licensed research and clinical evaluation only. Not dosing guidance.
Reconstitution
Bacteriostatic water (0.9% benzyl alcohol) or sterile water. Add diluent slowly along the vial wall — do not inject directly onto the lyophilized cake. Swirl gently until fully dissolved.
Storage
Lyophilized: −20°C long term; 2–8°C short term (weeks). Protect from light.Reconstituted: 2–8°C, generally up to 14–28 days depending on compound.
Quality
≥99% purity by HPLC. Identity confirmed by mass spectrometry. Independent third-party verification on every lot. COA available per lot.
Handling notes —Avoid repeated freeze–thaw cycles. Do not shake vigorously after reconstitution.
Need a full protocol brief?
Reconstitution worksheets, concentration reference cards, and sample COA for verified accounts.
05 — Comparative
See molecular profile, pharmacokinetics, and handling next to related compounds in the same family.
06 — Citations
The following sources are representative of the literature describing Melanotan II. A full annotated citation list with PubMed identifiers is available on request.
See also the glossary of research terms and the full peptide library.
cGMP facility · Third-party tested · Cold-chain shipping · 24-hour COA on request