Reference Protocols
Editorial Protocol Library
Curated reference protocols organized by indication. Each entry includes mechanism rationale, typical reference windows, and peer-reviewed citations. Intended as a starting point for clinician review — not as treatment recommendations.
Metabolic
Weight Management Protocol
Reference Stack
Tirzepatide + Cagrilintide
Typical Window
12–16 weeks
Mechanism Rationale
Dual incretin agonism (GIP/GLP-1) paired with amylin co-agonism for layered effects on glycemic control, gastric emptying, and satiety signaling. Reference window reflects published clinical literature on titration and stabilization.
Key References
- — Jastreboff et al., NEJM 2022
- — Frias et al., Lancet 2021
- — Enebo et al., Lancet 2021
Regenerative
Soft-Tissue Recovery Protocol
Reference Stack
BPC-157 + TB-500
Typical Window
4–8 weeks
Mechanism Rationale
Cytoprotective pentadecapeptide combined with thymosin beta-4 fragment for layered effects on angiogenesis, cellular migration, and fibroblast activity. Commonly referenced in musculoskeletal recovery literature.
Key References
- — Sikiric et al., Curr Pharm Des 2018
- — Goldstein et al., Ann NY Acad Sci 2012
GH Axis
GH Axis Support Protocol
Reference Stack
Ipamorelin + CJC-1295
Typical Window
8–12 weeks
Mechanism Rationale
Selective ghrelin receptor agonism paired with GHRH analog for pulsatile growth hormone release while preserving physiological feedback. Reference window reflects observed IGF-1 stabilization curves.
Key References
- — Raun et al., Eur J Endocrinol 1998
- — Teichman et al., J Clin Endocrinol Metab 2006
Longevity
Mitochondrial Support Protocol
Reference Stack
SS-31 (Elamipretide)
Typical Window
6–12 weeks
Mechanism Rationale
Cardiolipin-targeted tetrapeptide for inner mitochondrial membrane stabilization and electron transport chain efficiency. Active investigation in mitochondrial myopathies and age-related decline.
Key References
- — Szeto, Br J Pharmacol 2014
- — Karaa et al., Neurology 2018
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Editorial Reference Only
All protocols are editorial reference summaries drawn from published clinical literature. They are not medical advice, treatment recommendations, or substitutes for clinician judgment. Reference windows reflect commonly reported ranges and do not constitute dosing guidance.